About Presude
Presude Life sciences is led by biopharma professionals with global experience, offering integrated drug discovery and development services. As a research-driven organization, they specialize in medicinal chemistry, custom synthesis, and biological profiling across therapeutic areas such as Autoimmunity, Inflammation, Oncology/Immuno-oncology, and Anti-infectives. Addressing diverse client needs throughout the drug discovery and development value chain, Presude's expert scientists excel in transforming hits into molecules with drug-like properties. They are known for focused library design, screening, and de novo synthesis, with modifications aimed at improving selectivity, potency, and stability. As a valued partner, Presude has successfully helped numerous clients in the biopharmaceutical industry design and synthesize new drugs, efficiently progressing them through development.
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Services
Integrated Drug Discovery
Leverage the proficiency of their adept medicinal chemistry and biology teams. Accelerate the identification of preclinical candidates by entrusting your discovery, hit identification, hit-to-lead, and lead optimization to their highly efficient integrated team. Their dedicated team ensures a seamless implementation, providing ongoing support to optimize and elevate the effectiveness of your IDD program.
Chemistry Services
Presude scientists are experts at taking hits generated either by screening or fragment-based techniques and converting them into molecules with drug-like properties. They routinely perform focused library design and screening coupled with de novo synthesis including exploration into novel chemical space. They extend our capabilities beyond synthesis, providing expertise in process development and the creation of streamlined synthesis routes tailored for scalable production.
Consultation
Presude’s consultative services group possesses >100 man-years of scientific experience in the development of drugs in various therapeutic areas. They have long standing project engagements with leading biopharmaceutical companies in the areas of oncology, infectious and cardiovascular diseases. Their customized consulting solutions help empower our clients to make smart decisions as they move assets through discovery, preclinical and clinical development.
ADME DMPK Studies
Initiating ADME DMPK studies during the early stages of discovery can aid in mitigating compound failures. These studies serve to validate toxicology assessments, support safety evaluations before First-in-Human (FIH) trials, and provide insights into the potential for drug-drug interactions (DDIs).
Screening of Biologics
Presude provides services customized to your target of interest that are biologically-relevant, MoA reflective, robust assays with high reproducibility in a high-throughput format to expedite your biologics screening process.
Pharmacology
Advancing your drug discovery process is their goal. Presude Lifesciences is committed to adding value to your journey by providing customized biological assay development. Their assay development and screening biologists combine target class and cell biology expertise with state-of-the-art instrumentation to provide services tailored to your requirements. Their scientists can help you select the right type of assays in different therapeutic areas: oncology, immunology, autoimmunity and infectious diseases.
Target Dossier Consulting
Their target dossier services are designed to offer a thorough due diligence to therapeutic targets before embarking on the long, expensive, and winding road to discovering a novel drug. The dossiers they provide go beyond a mere compilation of information available from the web. Instead, they offer a strategic perspective on current gaps in the therapeutic area, liabilities, drawbacks of current drugs, and suggestions on differentiation over marketed drugs.
Translation Sciences
Presude’s collaboration with local hospitals and tissue/organ repositories enables access to patient samples (blood, tissues, saliva, BALF). Their comprehensive offering working with patient samples enables you to design and conduct the most efficient clinical proof-of-concept studies and reach go/no-go decisions.
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